Yes, here's how you can set up.

1. On your computer, open your Gmail.
2. 2. In the top right, click Settings.
3. Scroll down to the Vacation responder section.
4. Select Vacation responder on.
5. Fill in the date range, subject, and message.
6. Under your message, check the box if you only want your contacts to see your vacation reply.
7. At the bottom of the page, click Save Changes.

Note: If you have a Gmail signature, it will be shown at the bottom of your vacation response.

See also: Out of office or vacation reply (Google Account Help)

https://support.google.com/mail/answer/25922?co=GENIE.Platform%3DDesktop&hl=en